First approval of Cadonilimab (PD-1/CTLA-4 bispecific) published in Drugs, a peer-reviewed medical journal

HONG KONG, Aug. 26, 2022 /PRNewswire/ -- Akeso, Inc. (9926.HK) ("Akeso"), a biopharmaceutical company committed to the research, development, manufacturing and commercialization of either first-in-class or best-in-class therapies, announced a review article featuring on Cadonilimab, a first-in-class PD-1/CTLA-4 bi-specific antibody developed by the company, was published in Drugs, a peer-reviewed medical journal specializing in pharmaceutics.

Article link: https://link.springer.com/article/10.1007/s40265-022-01761-9The article provides an in-depth and comprehensive summary of the prospective drug design rationale of Cadonilimab, clinical trials progress in different tumors, and milestones in the development of Cadonilimab leading to its first approval.Cadonilimab received its first approval on June 2022 in China for use in patients withrelapsed or metastatic cervical cancer (r/m CC) who have progressed on or after platinum-based chemotherapy. Cadonilimab is the globally first dual immune checkpoint inhibitor bi-specific antibody approved for marketing. It is worth mentioning that the approval of Cadonilimab not only marks China's innovative biotech companies starting to reap the fruits after years of R&D investments but also demonstrates that Chinese biotech companies represented by Akeso are closing the gap with global pharmaceutical companies rapidly in innovative drug development.