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Haoma Medica Announces Plenary Presentation for NaQuinate, a Potential Novel Treatment for Osteoporosis, at ASBMR 2020 Annual Meeting

LONDON, Sept. 11, 2020 /PRNewswire/ -- Haoma Medica announced a presentation made today at the 2020 American Society for Bone and Mineral Research:
Haoma Medica Announces Plenary Presentation for NaQuinate, a Potential Novel Treatment for Osteoporosis, at ASBMR 2020 Annual Meeting
Dr Andrew Pitsillides,A Professor of Skeletal Dynamics at the Royal Veterinary College, LondonA presented 'NaQuinate: A Drug that Selectively Synergizes with Mechanical Loading Stimuli In Vivo to Generate Greater Cortical Bone Mass and Architectural Modifications'.Previous studies have shown NaQuinate, a naphthoquinone carboxylic acid, to protect against reduction in bone quality and quantity occurring in response to ovariectomy in rat and mouse models. In the data presented today using an applied mechanical mouse loading model, NaQuinate synergized the body's normal response to loading (a surrogate for greater weight-bearing exercise) to generate significant increases in cortical bone mass (increased cross sectional area, reductions in cortical porosity) and J-score (predictor of bone strength) compared to loading alone; the combined effect of loading and NaQuinate was much greater than additive. The bone studied here was the tibia in the leg, one of the largest bones in the body and where cortical bone is the core component.'There are 3 ways to maintain bone quality and strength to resist fracture - stop bone loss, build mass and enhance the topographical changes to optimize and enhance weight-bearing roles. It may be that NaQuinate can achieve a balance of all three to treat osteoporosis and better maintain healthy aging,' said Professor Andrew Pitsillides, presenting author.
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