Multiple NICUs Showed Improved Growth & Lung Health in Premature Infants by Fortifying Feeds Safely in the First Days of Life with Prolactaa??s 100% Human Milk-Based Fortifiers

DUARTE, Calif., July 14, 2020 (GLOBE NEWSWIRE) -- Prolacta Bioscience, the worlda??s leading hospital provider of 100% human milk-based nutritional products, announced today the results of an independent, multicenter study of 394 extremely premature infants that demonstrated the benefits of an early versus late fortification feeding protocol. According to this study, the use of Prolactaa??s fortifiers in the first days of life helped premature infants achieve better growth and is associated with significantly less bronchopulmonary dysplasia (BPD)/chronic lung disease of prematurity (CLD), all without compromising safety. The study was led by author Robert K. Huston, M.D., and published in the Journal of Neonatal-Perinatal Medicine.
Lung health is an important short- and long-term outcome for preterm infants. However, because the lungs are among the last organs to mature in the womb, lung dysfunction such as BPD/CLD is common in preterm infants. Neonatal nutrition is a critical consideration in addressing lung health; however, many neonatal intensive care units (NICUs) delay adding a fortifier to extremely premature infantsa?? feeds due to the risk of complications associated with cow milk-based fortifiers.This study showed that adding Prolactaa??s human milk-based fortifiers in the first days of life resulted in greater growth velocities for weight and head circumference and a 15% reduction in BPD/CLD (P = 0.008), compared with infants who received late fortification.These benefits were seen without an increase in complications. Infants who received early fortification in the study did not show significant increases in necrotizing enterocolitis (NEC) or surgical NEC, life-threatening complications that limit the use of early fortification with cow milk-based fortifiers.The Huston Early Fortification Study investigators compared the outcomes of infants born weighing 500 to 1,250 g whose feedings included mothera??s own milk, donor milk when needed, and Prolactaa??s human milk-based fortifiers at less than 60 mL/kg/day (early fortification) or greater than 60 mL/kg/day (late fortification).
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