ISCHEMIA Trial Finds No Evidence of Lower Cardiac Event Rates in Patients Treated with Heart Procedures, but Better Quality of Life

BROOKLYN, N.Y., Nov. 16, 2019 /PRNewswire/ --A A federally funded, international study found no evidence that patients with severe but stable heart disease who underwent heart procedures experienced lower rates of major, disease-related events compared to those treated with medications and lifestyle changes alone.Presented November 16 at the American Heart Association's Scientific Sessions 2019, the study found that patients that underwent routine, invasive procedures a?? like stent implants or bypass surgery a?? when compared with patients that received only medications (e.g. aspirin, statins) and lifestyle advice, saw no reduction in the rate of occurrence for a group of five events: cardiovascular death, heart attack, hospitalization for unstable angina, hospitalization for heart failure, or resuscitation after cardiac arrest.Called ISCHEMIA (International Study of Comparative Health Effectiveness with Medical and Invasive Approaches), the trial also found no overall difference between the two treatment strategies in the rates of cardiovascular death or heart attack.At the same time, the investigators found that for patients overall with symptoms of angina a?? the chest pain caused by restricted blood flow to heart muscle a?? invasive treatments resulted in better symptom relief and quality of life that persisted for four years. Among those with daily or weekly angina at the start of the study, 50 percent of those treated invasively were angina- free after a year, compared to 20 percent of those treated with medications and lifestyle advice alone.
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